PancrePAP assay kit
The Pancreatitis Associated Protein (PAP) is synthesized by the exocrine pancreas in the course of acute pancreatitis. It is found in the blood within 12hours of the onset of the pancreatitis episode. A multicenter study in the adult (Gastroenterology, 1994,106 : 728-734) has shown that :
- Patients presenting with a normal serum PAP value at admission generally do not develop complications. The range of normal serum PAP concentrations is 0-25ng/ml (median 12.5 ng/ml)
- An increase with time of serum PAP concentration reflects a progression of the disease.
- A decrease indicates that the acute phase of the crisis is ending.
Thus, analysis of the variations of the serum PAP level in a patient provides information on the progression of acute pancreatitis.
A kit for assaying PAP by ELISA, called PancrePAP is available from DYNABIO.
The kit allows PAP assay in human serum or plasma. It contains all reagents for 96 PAP assays and instructions for use. Its shelf life is 6 months.
The microtitration plate contains six 16-well bars, which can be used independently if a few assays have to be made at a time.